We consider a platform facilitating trade between sellers and buyers with the objective of maximizing consumer surplus. In many such platforms prices are set by revenue-maximizing sellers, but the platform may influence prices through its promotion policy (e.g., increasing demand to a certain product by assigning to it a prominent position on the webpage), and…
Asymmetric power GARCH models have been widely used to study the higher order moments of financial returns, while their quantile estimation has been rarely investigated. This paper introduces a simple monotonic transformation on its conditional quantile function to make the quantile regression tractable. The asymptotic normality of the resulting quantile estimators is established under either…
In this Element and its accompanying Element, Matias D. Cattaneo, Nicolas Idrobo, and Rocio Titiunik provide an accessible and practical guide for the analysis and interpretation of Regression Discontinuity (RD) designs that encourages the use of a common set of practices and facilitates the accumulation of RD-based empirical evidence. In this Element, the authors discuss…
We present a general framework for studying regularized estimators; such estimators are pervasive in estimation problems wherein “plug-in” type estimators are either ill-defined or ill-behaved. Within this framework, we derive, under primitive conditions, consistency and a generalization of the asymptotic linearity property. We also provide data-driven methods for choosing tuning parameters that, under some conditions,…
The adhesion of biomembranes is mediated by the binding of membrane-anchored receptor and ligand proteins. The proteins can only bind if the separation between apposing membranes is sufficiently close to the length of the protein complexes, which leads to an interplay between protein binding and membrane shape. In this article, we review current models of…
In animal groups, individual decisions are best characterised by probabilistic rules. Furthermore, animals of many species live in small groups. Probabilistic interactions among small numbers of individuals lead to a so called intrinsic noise at the group level. Theory predicts that the strength of intrinsic noise is not a constant but often depends on the…
Averaging amplitudes over consecutive time samples within a time-window is widely used to calculate the amplitude of an event-related potential (ERP) for cognitive neuroscience. Objective determination of the time-window is critical for determining the ERP component. Clustering on the spatio-temporal ERP data can obtain the time-window in which the consecutive time samples topographies are expected…
Parallel developments in neuroscience and deep learning have led to mutually productive exchanges, pushing our understanding of real and artificial neural networks in sensory and cognitive systems. However, this interaction between fields is less developed in the study of motor control. In this work, we develop a virtual rodent as a platform for the grounded…
Peristalsis enables transport of the food bolus in the gut. Here, I show by dynamic ex-vivo intra-cellular calcium imaging on living embryonic gut transverse sections that the most primitive form of peristalsis that occurs in the embryo is the result of inter-cellular, gap-junction dependent calcium waves that propagate in the circular smooth muscle layer. I…
Understanding age-group dynamics of infectious diseases is a fundamental issue for both scientific study and policymaking. Age-structure epidemic models were developed in order to study and improve our understanding of these dynamics. By fitting the models to incidence data of real outbreaks one can infer estimates of key epidemiological parameters. However, estimation of the transmission…